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Anti-PROM1 (scFv-Sap) immunotoxin
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This immunotoxin was achieved by conjugating/fusing the Anti-PROM1 scFv to saporin. It was expressed in CHO and purified with affinity chromatography. This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. https://www.creativebiolabs.net/Anti-PROM1-scFv-Sap-immunotoxin-17545.htm.
