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Anti-Cckbr (scFv-PE) immunotoxin
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This immunotoxin was achieved by conjugating/fusing the Anti-Cckbr scFv to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to gastrin/cholecystokinin subtype 2 receptor (CCK2R), This gene encodes a G protein-coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK a...https://www.creativebiolabs.net/Anti-Cckbr-scFv-PE-immunotoxin-16761.htm.
