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Anti-EGFR (scFv-Gel) immunotoxin
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This immunotoxin was achieved by conjugating/fusing the Anti-EGFR scFv to gelonin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein. https://www.creativebiolabs.net/Anti-EGFR-scFv-Gel-immunotoxin-16988.htm.
