Afucoâ„¢ Anti-Human CD44 ADCC Theraputic Antibody (RG7356), ADCC Enhanced

Anti-CD44 ADCC Enhanced Antibody (RG7356) is an ADCC enhanced antibody produced by our Afucoâ„¢ platform. RG7356 is a humanized antibody targeting the constant region of CD44 that shows antitumor efficacy in mice implanted with CD44-expressing tumors such as MDA-MB-231 breast cancer cells. Short-term treatment of tumor-bearing mice with RG7356 resulted in modifications of the MAPK pathway in the responsive model, although no effects on downstream phosphorylation were observed in a nonresponsive xenograft model.
https://www.creativebiolabs.net/Anti-CD44-ADCC-Enhanced-Antibody-RG7356-20428.htm