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anti-HIgG(Fc)-C-MMAE ADC
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This ADC product is comprised of an anti-human IgG Fc specific polyclonal antibody conjugated via a cleavable linker to MMAE. The antibody portion is a secondary antibody and the drug portion, MMAE, is a cytotoxic small molecule which binds to tubulins, interrupts microtubule dynamics, and induces cell death. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates. http://www.creative-biolabs.com/adc/target-igg-fc-55.htm
