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Anti-CD37 scFv h(CD3ζ) CART, pCDCAR1
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https://www.creative-biolabs.com/car-t/pcdcar1-cd37-h-ζ-t-135.htm The vector of anti-CD37 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD37. The T cells are genetically modified through transduction with a vector expressing scFv of anti-CD37 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of B cell malignancies, such as chronic lymphocytic leukemia (CLL), B cell non-Hodgkin lymphoma (B cell NHL), hairy cell leukemia (HCL), acute lymphoblastic leukemia (ALL) and lymphoplasmacytic lymphoma.


