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Anti-EGFR scFv h(CD28-CD3ζ) CART, pCDCAR1
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https://www.creative-biolabs.com/car-t/pcdcar1egfr-h-28ζ-t-233.htm The vector of anti-EGFR chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human EGFR. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGFR antibody linked to a CD28 transmembrane domain/ endodomain and CD3-zeta signaling domains. And the vector product was designed for the immune response cells in preparation of drugs for treatment of malignant tumor and virus infected diseases.
