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Anti-NY-ESO-1 scFv h(CD4-FcεRIγ) CART, pCDCAR1
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https://www.creative-biolabs.com/car-t/pcdcar1-ny-eso-1-h-4γ-t-222.htm The vector of anti-NY-ESO-1 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human NY-ESO-1. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-NY-ESO-1 antibody linked to CD4 transmembrane domain and FcεRIγ signaling domains. And the vector product was designed for the treatment of metastatic melanoma and synovial cell sarcoma.
